Article

Estrogen receptor inhibition enhances cold-induced adipocyte beiging and glucose sensitivity

2017-12-06

Abstract excerpt

Low estrogen states, exemplified by postmenopausal women, are associated with increased adiposity and metabolic dysfunction. We recently reported a paradox, in which a conditional estrogen receptor-alpha (ERα) mutant mouse shows a hyper-metabolic phenotype with enhanced brown/beige cell formation (“browning/beiging”). These observations led us to consider that although systemic deficiency of estrogen or ERα in mic...

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Literature Corpus work: 093f709d-1e25-507e-9f67-dc501fb680cc
DOI: 10.1101/229591

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