Article
Regulation of monoamine levels by typical and atypical antipsychotics in Caenorhabditis elegans mutant for nuclear distribution element genes.
Neurochemistry international - 1 Jul 2021
Campeiro Joana D'Arc, Nani João V, Monte Gabriela G, Almeida Priscila G C, Mori Marcelo A, Hayashi Mirian A F
Abstract excerpt
Mammalian nuclear distribution genes encode proteins with essential roles in neuronal migration and brain formation during embryogenesis. The implication of human nuclear distribution genes, namely nudC and NDE1 (Nuclear Distribution Element 1)/NDEL1 (Nuclear Distribution Element-Like 1), in psychiatric disorders including schizophrenia and bipolar disorder, has been recently described. The partial loss of NDEL1...
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