Article
Copy number variation underlies complex phenotypes in domestic dog breeds and other canids.
Genome research - 1 May 2021
Serres-Armero Aitor, Davis Brian W, Povolotskaya Inna S, Morcillo-Suarez Carlos, Plassais Jocelyn, Juan David, Ostrander Elaine A, Marques-Bonet Tomas
Abstract excerpt
Extreme phenotypic diversity, a history of artificial selection, and socioeconomic value make domestic dog breeds a compelling subject for genomic research. Copy number variation (CNV) is known to account for a significant part of inter-individual genomic diversity in other systems. However, a comprehensive genome-wide study of structural variation as it relates to breed-specific phenotypes is lacking. We have...
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