Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.

doi:10.1186/s13059-023-03023-7

Article

Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.

Genome biology - 15 Aug 2023

Meadows Jennifer R S, Kidd Jeffrey M, Wang Guo-Dong, Parker Heidi G, Schall Peter Z, Bianchi Matteo, Christmas Matthew J, Bougiouri Katia, Buckley Reuben M, Hitte Christophe, Nguyen Anthony K, Wang Chao, Jagannathan Vidhya, Niskanen Julia E, Frantz Laurent A F, Arumilli Meharji, Hundi Sruthi, Lindblad-Toh Kerstin, Ginja Catarina, Agustina Kadek Karang, André Catherine, Boyko Adam R, Davis Brian W, Drögemüller Michaela, Feng Xin-Yao, Gkagkavouzis Konstantinos, Iliopoulos Giorgos, Harris Alexander C, Hytönen Marjo K, Kalthoff Daniela C, Liu Yan-Hu, Lymberakis Petros, Poulakakis Nikolaos, Pires Ana Elisabete, Racimo Fernando, Ramos-Almodovar Fabian, Savolainen Peter, Venetsani Semina, Tammen Imke, Triantafyllidis Alexandros, vonHoldt Bridgett, Wayne Robert K, Larson Greger, Nicholas Frank W, Lohi Hannes, Leeb Tosso, Zhang Ya-Ping, Ostrander Elaine A

Abstract excerpt

BACKGROUND: The international Dog10K project aims to sequence and analyze several thousand canine genomes. Incorporating 20 × data from 1987 individuals, including 1611 dogs (321 breeds), 309 village dogs, 63 wolves, and four coyotes, we identify genomic variation across the canid family, setting the stage for detailed studies of domestication, behavior, morphology, disease susceptibility, and genome architecture...

Topics

Dogs
Animals
Wolves
Chromosome Mapping
Alleles

Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.

Abstract excerpt

Topics

Discuss the evidence