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Genomic characteristics of cattle copy number variations.

BMC genomics - 23 Feb 2011

Hou Yali, Liu George E, Bickhart Derek M, Cardone Maria Francesca, Wang Kai, Kim Eui-Soo, Matukumalli Lakshmi K, Ventura Mario, Song Jiuzhou, VanRaden Paul M, Sonstegard Tad S, Van Tassell Curt P

Abstract excerpt

BACKGROUND: Copy number variation (CNV) represents another important source of genetic variation complementary to single nucleotide polymorphism (SNP). High-density SNP array data have been routinely used to detect human CNVs, many of which have significant functional effects on gene expression and human diseases. In the dairy industry, a large quantity of SNP genotyping results are becoming available and can be...

Topics

Animals
Breeding
Cattle
Comparative Genomic Hybridization
Gene Dosage
Genetic Markers
Genome
Genomics
Genotype
Pedigree
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

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Identifiers

PMID: 21345189
DOI: 10.1186/1471-2164-12-127
PMCID: PMC3053260

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