Article
A high-resolution integrated map of copy number polymorphisms within and between breeds of the modern domesticated dog.
BMC genomics - 16 Aug 2011
Nicholas Thomas J, Baker Carl, Eichler Evan E, Akey Joshua M
Abstract excerpt
BACKGROUND: Structural variation contributes to the rich genetic and phenotypic diversity of the modern domestic dog, Canis lupus familiaris, although compared to other organisms, catalogs of canine copy number variants (CNVs) are poorly defined. To this end, we developed a customized high-density tiling array across the canine genome and used it to discover CNVs in nine genetically diverse dogs and a gray wolf....
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