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Negative symptoms in schizophrenia: correlation with clinical and genetic factors.

Pharmacogenomics - 1 May 2021

Hajj Aline, Hallit Souheil, Chamoun Karam, Sacre Hala, Obeid Sahar, Haddad Chadia, Dollfus Sonia, Khabbaz Lydia Rabbaa

Abstract excerpt

Aim: Explore the possible association between clinical factors and genetic variants of the dopamine pathways and negative symptoms. Materials & methods: Negative symptoms were assessed in 206 patients with schizophrenia using the Arabic version of the self-evaluation of negative symptoms scale and the Positive and Negative Syndrome Scale. Genotyping for COMT, DRD2, MTHFR and OPRM1 genes was performed. Results:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33858192
DOI: 10.2217/pgs-2020-0171

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