Article
Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population.
PloS one - 1 Jan 2015
Huang Er-Wen, Peng Long-Yun, Zheng Jin-Xiang, Wang Dan, Xu Qu-Yi, Huang Lei, Wu Qiu-Ping, Tang Shuang-Bo, Luo Bin, Liu Shui-Ping, Liu Xiao-Shan, Li Zhao-Hui, Quan Li, Li Yue, Shi He, Lv Guo-Li, Zhao Jian, Cheng Jian-Ding, Liu Chao
Abstract excerpt
The first genome-wide association study for coronary artery disease (CAD) in the Han Chinese population, we reported recently, had identified rs6903956 in gene ADTRP on chromosome 6p24.1 as a novel susceptibility locus for CAD. The risk allele of rs6903956 was associated with decreased mRNA expression of ADTRP. To further study the correlation of ADTRP expression and CAD, in this study we evaluated the...
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