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Identification and validation of the clinical roles of the VHL-related LncRNAs in clear cell renal cell carcinoma

1 Jan 2021

Abstract excerpt

Accumulating evidence suggests that lncRNAs (long non-coding RNAs) function as oncogenes or tumor suppressor genes in ccRCC (clear cell renal cell carcinoma). Although VHL (Von Hippel-Lindau) gene inactivation is by far the most common carcinogenic driving event in ccRCC, the roles of VHL-related lncRNAs in ccRCC remain unknown. In this study, using RNA-seq and clinical data in TCGA-KIRC (the Cancer Genome...

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PMID: 33854630
DOI: 10.7150/jca.55113

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