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Article

Development and validation of a VHL-associated immune prognostic signature for clear cell renal cell carcinoma

1 Dec 2020

Abstract excerpt

BACKGROUND: VHL mutation is the most common mutation in clear cell renal cell carcinoma (ccRCC). Here, we developed and validated an immune-related signature to predict the prognosis of ccRCC with VHL mutations. METHODS: VHL mutation status and RNA expression were analysed in the TCGA datasets and our cohort. LASSO Cox analysis was performed to develop an immune-related signature. Candidate genes for the...

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PMID: 33372609
DOI: 10.1186/s12935-020-01670-5

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