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Article

Nicotinate-curcumin inhibits AngII-induced vascular smooth muscle cell phenotype switching by upregulating Daxx expression.

Cell adhesion & migration - 1 Dec 2021

Sun Si-Yu, Cao Yu-Mei, Huo Yan-Jie, Qiu Fei, Quan Wen-Juan, He Chao-Ping, Chen Yu, Liao Duan-Fang, Tuo Qin-Hui

Abstract excerpt

Phenotypic switching is the main cause of the abnormal proliferation and migration of vascular smooth muscle cells (VSMCs). We previously showed that Daxx exerted negative regulatory effect on AngII-induced VSMC proliferation and migration. However, the function of Daxx in VSMC phenotype switching remained unknown. Nicotinate-curcumin (NC) is an esterification derivative of niacin and curcumin that can prevent...

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Identifiers

PMID: 33843453
DOI: 10.1080/19336918.2021.1909899
PMCID: PMC8043179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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