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Article

Analysis of overlapping genetic association in type 1 and type 2 diabetes.

Diabetologia - 1 Jun 2021

Inshaw Jamie R J, Sidore Carlo, Cucca Francesco, Stefana M Irina, Crouch Daniel J M, McCarthy Mark I, Mahajan Anubha, Todd John A

Abstract excerpt

AIMS/HYPOTHESIS: Given the potential shared aetiology between type 1 and type 2 diabetes, we aimed to identify any genetic regions associated with both diseases. For associations where there is a shared signal and the allele that increases risk to one disease also increases risk to the other, inference about shared aetiology could be made, with the potential to develop therapeutic strategies to treat or prevent...

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Topics

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Share to Alleles
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 33830302
DOI: 10.1007/s00125-021-05428-0
PMCID: PMC8099827

Genes

BCAR1
CTRB1
GLIS3
INS
PGM1
TMEM129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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