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Article

Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complications

3 Apr 2021

Abstract excerpt

The forkhead box O3a protein (FoxO3a) has been reported to regulate tumour invasion and migration, but little is known about the molecular mechanism or its role in trophoblast invasion and migration into the uterus. In this study, we aim to explore its role in trophoblast development and placenta-related pregnancy complications and the potential mechanism. Levels of FoxO3a and its phosphorylated form (p-FoxO3a)...

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PMID: 33811439
DOI: 10.1111/jcmm.16499

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