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AQP3 Influences Unexplained Recurrent Abortion by Regulating Trophoblast Cell Migration and Invasion via the METTL14 / IGF2BP1 / AQP3 / PI3K / AKT Pathway

29 Jan 2025

Abstract excerpt

Reduced trophoblast migration and invasion contribute to unexplained recurrent spontaneous abortion (URSA). Aquaporin 3 (AQP3) plays a crucial role in facilitating trophoblast migration and invasion during early pregnancy through fetal-maternal crosstalk. This study aimed to comprehensively investigate the mechanism involving AQP3 and its modulatory effects on human extravillous trophoblast (HTR-8/SVneo cells)...

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PMID: 39878312
DOI: 10.1111/jcmm.70325

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AQP3 Influences Unexplained Recurrent Abortion by Regulating Trophoblast Cell Migration and Invasion via the METTL14 / IGF2BP1 / AQP3 / PI3K / AKT PathwayPMID 39878312Read ↗

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