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Article

Role of IGF2BP3 in trophoblast cell invasion and migration

23 Jan 2014

Abstract excerpt

The insulin-like growth factor-2 mRNA-binding protein 3 (IGF2BP3) is a member of a highly conserved protein family that is expressed specifically in placenta, testis and various cancers, but is hardly detectable in normal adult tissues. IGF2BP3 has important roles in RNA stabilization and translation, especially during early stages of both human and mouse embryogenesis. Placenta is an indispensable organ in...

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PMID: 24457969
DOI: 10.1038/cddis.2013.545

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