Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ITGB3 is reduced in pregnancies with preeclampsia and its influence on biological behavior of trophoblast cells

25 Dec 2024

Abstract excerpt

BACKGROUND: Preeclampsia (PE) is a serious pregnancy complication associated with impaired trophoblast function. Integrin β3 (ITGB3) is a cell adhesion molecule that plays a role in cell movement. The objective of this study was to identify the biological function and expression level of ITGB3 in PE. METHODS: Cell proliferation, migration, invasion, adhesion, and apoptosis were estimated by CCK8 assay, transwell,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39721996
DOI: 10.1186/s10020-024-01050-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ITGB3 is reduced in pregnancies with preeclampsia and its influence on biological behavior of trophoblast cellsPMID 39721996Read ↗

IGFBP2 Modulates Trophoblast Function and Epithelial–Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling PathwaySemantic proximity Read ↗

BCAM Deficiency May Contribute to Preeclampsia by Suppressing the PIK3R6/p-STAT3 SignalingSemantic proximity Read ↗

Aquaporin 3 promotes human extravillous trophoblast migration and invasionSemantic proximity Read ↗

PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migrationSemantic proximity Read ↗

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsiaSemantic proximity Read ↗

Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complicationsSemantic proximity Read ↗

The aberrantly expressed miR-193b-3p contributes to preeclampsia through regulating transforming growth factor-β signalingSemantic proximity Read ↗

Differential Expression of Extracellular Matrix and Adhesion Molecules in Fetal-Origin Amniotic Epithelial Cells of Preeclamptic PregnancySemantic proximity Read ↗

Trophoblast Cell Subtypes and Dysfunction in the Placenta of Individuals with Preeclampsia Revealed by Single-Cell RNA SequencingSemantic proximity Read ↗

AQP3 Influences Unexplained Recurrent Abortion by Regulating Trophoblast Cell Migration and Invasion via the METTL14 / IGF2BP1 / AQP3 / PI3K / AKT PathwaySemantic proximity Read ↗

TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of PreeclampsiaSemantic proximity Read ↗

Overexpressed IncRNA GATA3-AS1 in Preeclampsia and Its Effects on Trophoblast Proliferation and Migration by the miR-488-3p/ROCK1 AxisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.