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Noninvasive Prenatal Paternity Testing with a Combination of Well-Established SNP and STR Markers Using Massively Parallel Sequencing.

Genes - 22 Mar 2021

Shen Xuefeng, Li Ran, Li Haixia, Gao Yu, Chen Hui, Qu Ning, Peng Dan, Wu Riga, Sun Hongyu

Abstract excerpt

Cell-free fetal DNA (cffDNA) from maternal plasma has made it possible to develop noninvasive prenatal paternity testing (NIPPT). However, most studies have focused on customized single nucleotide polymorphism (SNP) typing systems and few have used conventional short tandem repeat (STR) markers. Based on massively parallel sequencing (MPS), this study used a widely-accepted forensic multiplex assay system to...

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Identifiers

PMID: 33810139
DOI: 10.3390/genes12030454
PMCID: PMC8004970

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