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Noninvasive prenatal paternity testing by maternal plasma DNA sequencing in twin pregnancies.

Electrophoresis - 1 Jun 2020

Xie Yifan, Qu Ning, Lin Shaobin, Jiang Haojun, Zhang Yanyan, Zhang Xiuqing, Liang Hao, Chen Fang, Ou Xueling

Abstract excerpt

SNPs, combined with massively parallel sequencing technology, have proven applicability in noninvasive prenatal paternity testing (NIPPT) for singleton pregnancies in our previous research, using circulating cell-free DNA in maternal plasma. However, the feasibility of NIPPT in twin pregnancies has remained uncertain. As a pilot study, we developed a practical method to noninvasively determine the paternity of...

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PMID: 32249439
DOI: 10.1002/elps.202000036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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