Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort.

doi:10.1093/jac/dkad195

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Article

Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort.

The Journal of antimicrobial chemotherapy - 2 Aug 2023

Abdullahi Adam, Kida Ibrahim Musa, Maina Umar Abdullahi, Ibrahim Amina Husaini, Mshelia James, Wisso Haruna, Adamu Abdullahi, Onyemata James Ezenwa, Edun Martin, Yusuph Haruna, Aliyu Sani H, Charurat Man, Abimiku Alash'le, Abeler-Dorner Lucie, Fraser Christophe, Bonsall David, Kemp Steven A, Gupta Ravindra K

Abstract excerpt

BACKGROUND: Due to the high prevalence of resistance to NNRTI-based ART since 2018, consolidated recommendations from the WHO have indicated dolutegravir as the preferred drug of choice for HIV treatment globally. There is a paucity of resistance outcome data from HIV-1 non-B subtypes circulating across West Africa. AIMS: We characterized the mutational profiles of persons living with HIV from a cross-sectional...

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PMID: 37367727
DOI: 10.1093/jac/dkad195
PMCID: PMC10393879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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