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Article

Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a randomised controlled trial

1 Apr 2021

Abstract excerpt

In a RCT of 63 patients with COPD, 12 weeks of ICS/LABA therapy downregulated bronchial epithelial expression of the SARS-CoV-2-related genes ACE2 and ADAM17 compared to LABA alone. This may have implications for COVID-19 susceptibility/severity in COPD.https://bit.ly/3vZnBVO

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PMID: 33795322
DOI: 10.1183/13993003.00130-2021

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