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How corticosteroids control inflammation: Quintiles Prize Lecture 2005

10 Apr 2006

Abstract excerpt

Corticosteroids are the most effective anti-inflammatory therapy for many chronic inflammatory diseases, such as asthma but are relatively ineffective in other diseases such as chronic obstructive pulmonary disease (COPD). Chronic inflammation is characterised by the increased expression of multiple inflammatory genes that are regulated by proinflammatory transcription factors, such as nuclear factor-kappaB and...

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PMID: 16604091
DOI: 10.1038/sj.bjp.0706736

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