Article
alms1 mutant zebrafish do not show hair cell phenotypes seen in other cilia mutants.
PloS one - 1 Jan 2021
Parkinson Lauren, Stawicki Tamara M
Abstract excerpt
Multiple cilia-associated genes have been shown to affect hair cells in zebrafish (Danio rerio), including the human deafness gene dcdc2, the radial spoke gene rsph9, and multiple intraflagellar transport (IFT) and transition zone genes. Recently a zebrafish alms1 mutant was generated. The ALMS1 gene is the gene mutated in the ciliopathy Alström Syndrome a disease that causes hearing loss among other symptoms....
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