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Article

The role of cilia in the development, survival, and regeneration of hair cells.

Biology open - 15 Sept 2024

Boldizar Hope, Friedman Amanda, Stanley Tess, Padilla María, Galdieri Jennifer, Sclar Arielle, Stawicki Tamara M

Abstract excerpt

Mutations impacting cilia genes lead to a class of human diseases known as ciliopathies. This is due to the role of cilia in the development, survival, and regeneration of many cell types. We investigated the extent to which disrupting cilia impacted these processes in lateral line hair cells of zebrafish. We found that mutations in two intraflagellar transport (IFT) genes, ift88 and dync2h1, which lead to the...

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Share to Cell Survival
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Share to Hair Cells, Auditory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potential, Mitochondrial

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Source

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Identifiers

PMID: 39263863
DOI: 10.1242/bio.061690
PMCID: PMC11413933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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