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Article

Exploratory development of PCR-fluorescent probes in rapid detection of mutations associated with extensively drug-resistant tuberculosis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Sept 2021

Liang Jianqin, An Huiru, Zhou Jin, Liu Yuqin, Xiang Guangxin, Liu Yingying, Xing Wanli, Gong Wenping

Abstract excerpt

This study aims to evaluate the clinical value of PCR-fluorescent probes for detecting the mutation gene associated with extensively drug-resistant tuberculosis (XDR-TB). The molecular species identification of 900 sputum specimens was performed using polymerase chain reaction (PCR)-fluorescent probe. The mutations of the drug resistance genes rpoB, katG, inhA, embB, rpsL, rrs, and gyrA were detected. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33792806
DOI: 10.1007/s10096-021-04236-z

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