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Article

Clinical evaluation of Rega 8: an updated genotypic interpretation system that significantly predicts HIV-therapy response.

PloS one - 1 Jan 2013

Vercauteren Jurgen, Beheydt Gertjan, Prosperi Mattia, Libin Pieter, Imbrechts Stijn, Camacho Ricardo, Clotet Bonaventura, De Luca Andrea, Grossman Zehava, Kaiser Rolf, Sönnerborg Anders, Torti Carlo, Van Wijngaerden Eric, Schmit Jean-Claude, Zazzi Maurizio, Geretti Anna-Maria, Vandamme Anne-Mieke, Van Laethem Kristel

Abstract excerpt

INTRODUCTION: Clinically evaluating genotypic interpretation systems is essential to provide optimal guidance in designing potent individualized HIV-regimens. This study aimed at investigating the ability of the latest Rega algorithm to predict virological response on a short and longer period. MATERIALS METHODS: 9231 treatment changes episodes were extracted from an integrated patient database. The virological...

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PMID: 23613852
DOI: 10.1371/journal.pone.0061436
PMCID: PMC3629176

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