Article
Correlation analysis between JAK2, MPL, and CALR mutations in patients with myeloproliferative neoplasms of Chinese Uygur and Han nationality and their clinical characteristics.
The Journal of international medical research - 1 Nov 2018
Lang Tao, Nie Yuling, Wang Zengsheng, Huang Qin, An Li, Wang Yichun, Wufuer Guzailinuer, Maimaiti Aziguli, Fu Ling, Li Yan, Zhang Xiaoyan, Aisimutula Aihemaitijiang, Wang Xiaomin, Zhu Lin, Liu Hong, Mao Min
Abstract excerpt
BACKGROUND: Genetic factors play a role in the etiology of BCR-ABL-negative myeloproliferative neoplasms (MPNs). This study explored the relationship between mutations in the Janus kinase 2 gene ( JAK2), MPL, and the calreticulin gene ( CALR) in Uygur and Han Chinese patients with BCR-ABL fusion gene-negative MPN and corresponding clinical features. METHODS: A total of 492 BCR-ABL-negative MPN patients treated in...
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