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Article

Genome-wide DNA methylation and RNA expression differences correlate with invasiveness in melanoma cell lines.

Epigenomics - 1 Apr 2021

Motwani Jyoti, Rodger Euan J, Stockwell Peter A, Baguley Bruce C, Macaulay Erin C, Eccles Michael R

Abstract excerpt

Aims & objectives: The aim of this study was to investigate the role of DNA methylation in invasiveness in melanoma cells. Materials & methods: The authors carried out genome-wide transcriptome (RNA sequencing) and reduced representation bisulfite sequencing methylome profiling between noninvasive (n = 4) and invasive melanoma cell lines (n = 5). Results: The integration of differentially expressed genes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33781093
DOI: 10.2217/epi-2020-0440

Genes

AVPI1
BCL3
HMG20B
HORMAD2
NTSR1
ROBO2
SYNJ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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