Article
Hereditary and Sporadic Pancreatic Ductal Adenocarcinoma: Current Update on Genetics and Imaging.
Radiology. Imaging cancer - 1 Mar 2020
Morani Ajaykumar C, Hanafy Abdelrahman K, Ramani Nisha S, Katabathina Venkata S, Yedururi Sireesha, Dasyam Anil K, Prasad Srinivasa R
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is a genetically heterogeneous, biologically aggressive malignancy with a uniformly poor prognosis. While most pancreatic cancers arise sporadically, a small subset of PDACs develop in patients with hereditary and familial predisposition. Detailed studies of the rare hereditary syndromes have led to identification of specific genetic abnormalities that contribute to...
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