Article
Complement Genetic Variants and FH Desialylation in S. pneumoniae-Haemolytic Uraemic Syndrome.
Frontiers in immunology - 1 Jan 2021
Gómez Delgado Irene, Corvillo Fernando, Nozal Pilar, Arjona Emilia, Madrid Álvaro, Melgosa Marta, Bravo Juan, Szilágyi Ágnes, Csuka Dorottya, Veszeli Nóra, Prohászka Zoltán, Sánchez-Corral Pilar
Abstract excerpt
Haemolytic Uraemic Syndrome associated with Streptococcus pneumoniae infections (SP-HUS) is a clinically well-known entity that generally affects infants, and could have a worse prognosis than HUS associated to E. coli infections. It has been assumed that complement genetic variants associated with primary atypical HUS cases (aHUS) do not contribute to SP-HUS, which is solely attributed to the action of the...
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