Article
OX40L/OX40 Signal Promotes IL-9 Production by Mucosal MAIT Cells During Helicobacter pylori Infection.
Frontiers in immunology - 1 Jan 2021
Ming Siqi, Zhang Mei, Liang Zibin, Li Chunna, He Jianzhong, Chen Peiyu, Zhang Shunxian, Niu Xiaoli, Deng Shimei, Geng Lanlan, Zhang Guoliang, Gong Sitang, Wu Yongjian
Abstract excerpt
Mucosal associated invariant T (MAIT) cells play a critical role in Helicobacter pylori (H. pylori)-induced gastritis by promoting mucosal inflammation and aggravating mucosal injuries (1, 2). However, the underlying mechanism and key molecules involved are still uncertain. Here we identified OX40, a co-stimulatory molecule mainly expressed on T cells, as a critical regulator to promote proliferation and IL-9...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.