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Article

T cell co-stimulatory molecules: a co-conspirator in the pathogenesis of eosinophilic esophagitis?

Digestive diseases and sciences - 1 Jun 2013

Zhang Zili, Sferra Thomas J, Eroglu Yasemen

Abstract excerpt

Eosinophilic esophagitis (EoE) has become a common gastrointestinal disease. It is characterized by severe eosinophil infiltration in the esophagus. EoE is strongly associated with food allergy, asthma, atopic dermatitis, and other allergic diseases. T lymphocytes, especially Th2 cells, play an instrumental role in the development of allergic inflammation. Recent studies have shown that the ligation of...

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PMID: 23456499
DOI: 10.1007/s10620-013-2599-8

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