Article
H. pylori modulates DC functions via T4SS/TNFα/p38-dependent SOCS3 expression.
Cell communication and signaling : CCS - 6 Oct 2020
Sarajlic Muamera, Neuper Theresa, Vetter Julia, Schaller Susanne, Klicznik Maria M, Gratz Iris K, Wessler Silja, Posselt Gernot, Horejs-Hoeck Jutta
Abstract excerpt
BACKGROUND: Helicobacter pylori (H. pylori) is a gram-negative bacterium that chronically infects approximately 50% of the world's human population. While in most cases the infection remains asymptomatic, 10% of infected individuals develop gastric pathologies and 1-3% progress to gastric cancer. Although H. pylori induces severe inflammatory responses, the host's immune system fails to clear the pathogen and H....
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