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Article

An immune window of opportunity to prevent childhood B cell leukemia.

Trends in immunology - 1 May 2021

Cobaleda César, Vicente-Dueñas Carolina, Sánchez-García Isidro

Abstract excerpt

The prevalence of childhood B cell acute lymphoblastic leukemia (B-ALL) is increasing, particularly in developed countries. There is no clear explanation for this increment, but recent data suggest that, besides genetic predisposition, stress in the immune system (e.g., an infection) might have an important role in B-ALL leukemogenesis. Here, we speculate on how this knowledge might impact B-ALL prevention...

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Share to Genetic Predisposition to Disease
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Identifiers

PMID: 33773925
DOI: 10.1016/j.it.2021.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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