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Article

Loss-of-Function Variants in the SYNPO2L Gene Are Associated With Atrial Fibrillation

9 Mar 2021

Abstract excerpt

Multiple genome-wide association studies (GWAS) have identified numerous loci associated with atrial fibrillation (AF). However, the genes driving these associations and how they contribute to the AF pathogenesis remains poorly understood. To identify genes likely to be driving the observed association, we searched the FinnGen study consisting of 12,859 AF cases and 73,341 controls for rare genetic variants...

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PMID: 33768119
DOI: 10.3389/fcvm.2021.650667

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