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Article

Knockdown of ZEB1 reverses cancer stem cell properties in prostate cancer cells

10 Mar 2021

Abstract excerpt

Prostate cancer (PCa) is the second most diagnosed type of cancer in men worldwide. Advanced PCa is resistant to conventional therapies and high recurrence has been associated with high rates of metastasis. Cancer stem cells (CSCs) have been proposed to be responsible for this, due to their ability of self‑renewal and differentiation into other cell types. Zinc finger E‑box‑binding homeobox 1 (ZEB1), a...

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PMID: 33760173
DOI: 10.3892/or.2021.8009

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