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Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate

5 Feb 2020

Abstract excerpt

Abstract The basal cell compartment in many epithelial tissues is generally believed to serve as an important pool of stem cells. However, basal cells are heterogenous and the stem cell subpopulation within basal cells is not well elucidated. Here we uncover that the core epithelial-to-mesenchymal transition (EMT) inducer Zeb1 is expressed in a prostate basal cell subpopulation. The Zeb1 + prostate epithelial...

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PMID: 32024836
DOI: 10.1038/s41467-020-14296-y

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