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Association of FTO gene methylation with incident type 2 diabetes mellitus: A nested case-control study.

Gene - 20 Jun 2021

Huang Shengbing, Qin Pei, Chen Qing, Zhang Dongdong, Cheng Cheng, Guo Chunmei, Li Quanman, Zhou Qionggui, Tian Gang, Qie Ranran, Han Minghui, Wu Xiaoyan, Yang Xingjin, Feng Yifei, Li Yang, Zhang Yanyan, Wu Yuying, Liu Dechen, Lu Jie, Zhang Ming, Zhao Yang, Hu Dongsheng

Abstract excerpt

OBJECTIVES: This study aimed to investigate the association of FTO methylation level with type 2 diabetes mellitus (T2DM) in a nested case-control study. METHODS: This nested case-control study included 287 pairs of T2DM cases and controls identified from a rural Chinese cohort study with a 6-year follow-up. Controls were matched to the cases on a 1:1 basis by age, sex, ethnicity, marital status, and residence....

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33753148
DOI: 10.1016/j.gene.2021.145585

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