Genome wide analysis reveals association of a FTO gene variant with epigenetic changes.

doi:10.1016/j.ygeno.2011.12.007

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Article

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes.

Genomics - 1 Mar 2012

Almén Markus Sällman, Jacobsson Josefin A, Moschonis George, Benedict Christian, Chrousos George P, Fredriksson Robert, Schiöth Helgi B

Abstract excerpt

Variants of the FTO gene show strong association with obesity, but the mechanisms behind this association remain unclear. We determined the genome wide DNA methylation profile in blood from 47 female preadolescents. We identified sites associated with the genes KARS, TERF2IP, DEXI, MSI1, STON1 and BCAS3 that had a significant differential methylation level in the carriers of the FTO risk allele (rs9939609). In...

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Identifiers

PMID: 22234326
DOI: 10.1016/j.ygeno.2011.12.007

Genes

FTO
BCAS3
DEXI
MSI1
STON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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