Article
The age of developing diabetes and FTO polymorphisms (rs9939609, rs1421085, and rs9930506).
Endokrynologia Polska - 1 Jan 2017
Grzeszczak Władysław, Molsa Maciej, Tłuczykont Marek, Markowicz Anna, Swoboda Ryszard, Biedak Marta, Kałuża Anna, Sirek Sebastian, Strojek Krzysztof
Abstract excerpt
INTRODUCTION: Type 2 diabetes (T2DM) is a common complex metabolic disorder that has a strong genetic predisposition. Fat mass and obesity-associated protein (FTO) is one of the genes of interest to us. Hypomethylation of a CpG site in the FTO gene was significantly associated with the risk of T2DM. The aim of the study was to find the answer to the question of whether the polymorphism changes of the FTO gene in...
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