Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of a typing model for diffuse large B-cell lymphoma based on B-cell receptor repertoire sequencing.

BMC cancer - 22 Mar 2021

Jiang Wenhua, Wang Hailong, Zhou Shiyong, Zhu Guoqing, Gao Mingyou, Zhao Kuo, Zhang Limeng, Xie Xiaojing, Zhao Ning, Tian Caijuan, Zhang Zhenzhen, Yan Fang, Pan Yi, Liu Pengfei

Abstract excerpt

BACKGROUND: The purpose of this study was to construct a new typing model for diffuse large B-cell lymphoma (DLBCL) patients based on the B-cell receptor (BCR) and explore its potential molecular mechanism. METHODS: BCR repertoire sequencing and whole-exome sequencing were performed on formalin-fixed paraffin-embedded samples from 12 DLBCL patients. Subsequently, a typing model was built with cluster analysis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Antigens, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cluster Analysis

Share to Exome Sequencing

Share to Lymphoma, Large B-Cell, Diffuse

Share to Methyltransferases

Share to Receptors, Antigen, B-Cell

Share to Seminal Plasma Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33752626
DOI: 10.1186/s12885-021-08015-z
PMCID: PMC7986026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of a typing model for diffuse large B-cell lymphoma based on B-cell receptor repertoire sequencing.PMID 33752626Read ↗

Characteristics of profiling the peripheral blood T‐cell receptor repertoire in patients with diffuse large B-cell lymphomaSemantic proximity Read ↗

B cell receptor (BCR) diversity and differential CDR3s usage as potential immune indictors of diffuse large B cell lymphoma (DLBCL) Running title: Vital roles of BCR traits in DLBCLSemantic proximity Read ↗

Gene set-based identification of two immune subtypes of diffuse large B cell lymphoma for guiding immune checkpoint blocking therapySemantic proximity Read ↗

Comprehensive characterization�of driver genes in diffuse large B�cell lymphomaSemantic proximity Read ↗

Simplified algorithm for genetic subtyping in diffuse large B-cell lymphomaSemantic proximity Read ↗

Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma.Semantic proximity Read ↗

Molecular heterogeneity in diffuse large B-cell lymphoma and its implications in clinical diagnosis and treatment.Semantic proximity Read ↗

Molecular pathogenesis of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Molecular pathogenesis and treatment strategy in diffuse large B-cell lymphoma.Semantic proximity Read ↗

Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B-cell lymphoma in a Japanese cohort.Semantic proximity Read ↗

Prognostic Analysis of Diffuse Large B-Cell Lymphoma Patients Based on Clinical Characteristics, TP53 Mutation Status, and Number of Co-mutated GenesSemantic proximity Read ↗

Cell-of-Origin Subtyping of Diffuse Large B-Cell Lymphoma by Using a qPCR-based Gene Expression Assay on Formalin-Fixed Paraffin-Embedded TissuesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.