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Article

Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer's Disease: The Shanghai Aging Study.

Current Alzheimer research - 1 Jan 2020

Xi Jianxiong, Ding Ding, Zhao Qianhua, Liang Xiaoniu, Zheng Li, Guo Qihao, Hong Zhen, Fu Hua, Xu Jianfeng, Xiao Qianyi

Abstract excerpt

BACKGROUND: Approximately 40 independent Single Nucleotide Polymorphisms (SNPs) have been associated with Alzheimer's Disease (AD) or cognitive decline in genome-wide association studies. OBJECTIVE: We aimed to evaluate the joint effect of genetic polymorphisms and environmental factors on the progression from Mild Cognitive Impairment (MCI) to AD (MCI-AD progression) in a Chinese community cohort. METHODS:...

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PMID: 32183673
DOI: 10.2174/1567205017666200317095608

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