Article
Validation of reported genetic risk factors for periodontitis in a large-scale replication study.
Journal of clinical periodontology - 1 Jun 2013
Schaefer Arne S, Bochenek Gregor, Manke Thomas, Nothnagel Michael, Graetz Christian, Thien Anneke, Jockel-Schneider Yvonne, Harks Inga, Staufenbiel Ingmar, Wijmenga Cisca, Eberhard Jörg, Guzeldemir-Akcakanat Esra, Cine Naci, Folwaczny Mathias, Noack Barbara, Meyle Joerg, Eickholz Peter, Trombelli Leonardo, Scapoli Chiara, Nohutcu Rahime, Bruckmann Corinna, Doerfer Christof, Jepsen Søren, Loos Bruno G, Schreiber Stefan
Abstract excerpt
AIM: Many studies investigated the role of genetic variants in periodontitis, but few were established as risk factors. We aimed to validate the associations of recent candidate genes in aggressive periodontitis (AgP). MATERIAL AND METHODS: We analysed 23 genes in 600 German AgP patients and 1441 controls on the Illumina custom genotyping array Immunochip. We tested a suggestive association in a Dutch and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
