Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional and Adaptive Significance of Promoter Mutations That Affect Divergent Myocardial Expressions of TRIM72 in Primates.

Molecular biology and evolution - 25 Jun 2021

Feng Yuanqing, Xu Hongzhan, Liu Jinghao, Xie Ning, Gao Lei, He Yanyun, Yao Yuan, Lv Fengxiang, Zhang Yan, Lu Jian, Zhang Wei, Li Chuan-Yun, Hu Xinli, Yang Ziheng, Xiao Rui-Ping

Abstract excerpt

Cis-regulatory elements play important roles in tissue-specific gene expression and in the evolution of various phenotypes, and mutations in promoters and enhancers may be responsible for adaptations of species to environments. TRIM72 is a highly conserved protein that is involved in energy metabolism. Its expression in the heart varies considerably in primates, with high levels of expression in Old World monkeys...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basal Metabolism
Share to Biological Evolution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Heart Rate

Share to Myocardium

Share to Oxidative Phosphorylation

Share to Primates

Share to Tripartite Motif Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33744959
DOI: 10.1093/molbev/msab083
PMCID: PMC8233513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional and Adaptive Significance of Promoter Mutations That Affect Divergent Myocardial Expressions of TRIM72 in Primates.PMID 33744959Read ↗

A comparison of gene expression and DNA methylation patterns across tissues and speciesSemantic proximity Read ↗

Tandem repeat variation in human and great ape populations and its impact on gene expression divergence.Semantic proximity Read ↗

Tandem repeat variation in human and great ape populations and its impact on gene expression divergenceSemantic proximity Read ↗

Heterotachy in mammalian promoter evolution.Semantic proximity Read ↗

Evolution of alternative splicing in primate brain transcriptomes.Semantic proximity Read ↗

Molecular diversity and phenotypic pleiotropy of ancient genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their contemporary impacts on pathophysiology of Modern Humans.Semantic proximity Read ↗

Identification of a Genomic Reservoir for New TRIM Genes in Primate GenomesSemantic proximity Read ↗

The contribution of evolutionarily volatile promoters to molecular phenotypes and human trait variation.Semantic proximity Read ↗

Comparative transcriptome in rhesus macaques and crab-eating macaquesSemantic proximity Read ↗

High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans.Semantic proximity Read ↗

Inter-species differences in response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzeesSemantic proximity Read ↗

Molecular Variation in Thermoregulatory Adaptation in Rodents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.