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Article

Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity.

Nature - 1 Dec 2021

Lucas Carolina, Vogels Chantal B F, Yildirim Inci, Rothman Jessica E, Lu Peiwen, Monteiro Valter, Gehlhausen Jeff R, Campbell Melissa, Silva Julio, Tabachnikova Alexandra, Peña-Hernandez Mario A, Muenker M Catherine, Breban Mallery I, Fauver Joseph R, Mohanty Subhasis, Huang Jiefang, Shaw Albert C, Ko Albert I, Omer Saad B, Grubaugh Nathan D, Iwasaki Akiko

Abstract excerpt

The emergence of SARS-CoV-2 variants with mutations in major neutralizing antibody-binding sites can affect humoral immunity induced by infection or vaccination1-6. Here we analysed the development of anti-SARS-CoV-2 antibody and T cell responses in individuals who were previously infected (recovered) or uninfected (naive) and received mRNA vaccines to SARS-CoV-2. While individuals who were previously infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34634791
DOI: 10.1038/s41586-021-04085-y
PMCID: PMC9348899

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