Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells.

Nature communications - 19 Mar 2021

Pascual-Reguant Anna, Köhler Ralf, Mothes Ronja, Bauherr Sandy, Hernández Daniela C, Uecker Ralf, Holzwarth Karolin, Kotsch Katja, Seidl Maximilian, Philipsen Lars, Müller Werner, Romagnani Chiara, Niesner Raluca, Hauser Anja E

Abstract excerpt

Innate lymphoid cells (ILCs) emerge in the last few years as important regulators of immune responses and biological processes. Although ILCs are mainly known as tissue-resident cells, their precise localization and interactions with the microenvironment are still unclear. Here we combine a multiplexed immunofluorescence technique and a customized computational, open-source analysis pipeline to unambiguously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective Tissue
Share to Image Processing, Computer-Assisted

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon Regulatory Factors

Share to Interleukin-7 Receptor alpha Subunit

Share to Lymphocytes

Share to Machine Learning

Share to Palatine Tonsil

Share to Spatial Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 33741932
DOI: 10.1038/s41467-021-21994-8
PMCID: PMC7979823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells.PMID 33741932Read ↗

The landscape of S100B+ and HLA-DR+ dendritic cell subsets in tonsils at the single cell level via high-parameter mappingSemantic proximity Read ↗

An Atlas of Cells in the Human TonsilSemantic proximity Read ↗

Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancerSemantic proximity Read ↗

In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging.Semantic proximity Read ↗

<i>ROSIE</i> : AI generation of multiplex immunofluorescence staining from histopathology imagesSemantic proximity Read ↗

The normal human lymph node cell classification and landscape defined by high-dimensional spatial proteomicsSemantic proximity Read ↗

Tissue-Specific Features of Innate Lymphoid CellsSemantic proximity Read ↗

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.Semantic proximity Read ↗

Spatial and Phenotypic Heterogeneity of ILC Subsets in Mouse Lung Under Type 2 Inflammatory Conditions.Semantic proximity Read ↗

Tissue-Specific Molecular Markers and Heterogeneity in Type 2 Innate Lymphoid CellsSemantic proximity Read ↗

Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination.Semantic proximity Read ↗

Tumor-infiltrating CD27 <sup>-</sup> IgD <sup>-</sup> regulatory B cells suppress cytotoxic CD8 <sup>+</sup> T cell responses in renal cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.