Article

<i>ROSIE</i> : AI generation of multiplex immunofluorescence staining from histopathology images

2024-11-11

Abstract excerpt

Hematoxylin and eosin (H&E) is a common and inexpensive histopathology assay. Though widely used and information-rich, it cannot directly inform about specific molecular markers, which require additional experiments to assess. To address this gap, we present ROSIE, a deep-learning framework that computationally imputes the expression and localization of dozens of proteins from H&E images. Our model is trained on...

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Literature Corpus work: 333962d3-7bc9-5846-84f8-c3c1a2055c3c
DOI: 10.1101/2024.11.10.622859

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