Article
Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma.
Clinics and research in hepatology and gastroenterology - 1 Nov 2021
Al-Khaykanee Ahmed Mudher, Abdel-Rahman Adel A-H, Essa Abdallah, Gadallah Abdel-Naser Abdel-Atty, Ali Bushra Hameed, Al-Aqar Afrodet Abdulrazaq, Badr Eman A E, Shehab-Eldeen Somaia
Abstract excerpt
BACKGROUND: Fibroblast growth factor receptor 2 (FGFR2) and trinucleotide repeat-containing 9 (TRNC9) gene polymorphisms have been associated with some cancers. We aimed to assess the association of FGFR2 rs2981582 and TRNC9 rs12443621 polymorphisms with hepatocellular cancer risk. METHODS: One hundred patients with HCV-induced HCC, 100 patients with chronic HCV infection, and 100 controls were genotyped for...
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