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Article

Some dystrophy phenotypes of dystrophin-deficient mdx mice are exacerbated by mild, repetitive daily stress.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2021

Lindsay Angus, Holm John, Razzoli Maria, Bartolomucci Alessandro, Ervasti James M, Lowe Dawn A

Abstract excerpt

Psychosocial stressors can cause physical inactivity, cardiac damage, and hypotension-induced death in the mdx mouse model of Duchenne muscular dystrophy (DMD). Because repeated exposure to mild stress can lead to habituation in wild-type mice, we investigated the response of mdx mice to a mild, daily stress to determine whether habituation occurred. Male mdx mice were exposed to a 30-sec scruff restraint daily...

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Source

Identifiers

PMID: 33734502
DOI: 10.1096/fj.202002500R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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