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Article

Genetic variation in aneuploidy prevalence and tolerance across Saccharomyces cerevisiae lineages.

Genetics - 15 Apr 2021

Scopel Eduardo F C, Hose James, Bensasson Douda, Gasch Audrey P

Abstract excerpt

Individuals carrying an aberrant number of chromosomes can vary widely in their expression of aneuploidy phenotypes. A major unanswered question is the degree to which an individual's genetic makeup influences its tolerance of karyotypic imbalance. Here we investigated within-species variation in aneuploidy prevalence and tolerance, using Saccharomyces cerevisiae as a model for eukaryotic biology. We analyzed...

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Identifiers

PMID: 33734361
DOI: 10.1093/genetics/iyab015
PMCID: PMC8049548

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