Article
Mass-Based Protein Phylogenetic Approach to Identify Epistasis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Downard Kevin M
Abstract excerpt
A mass-based protein phylogeny method, known as phylonumerics, is described to build phylogenetic-like trees using a purpose-built MassTree algorithm. These trees are constructed from sets of numerical mass map data for each protein without the need for gene or protein sequences. Such trees have been shown to be highly congruent with conventional sequence-based trees and provide a reliable means to study the...
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